Tag Archives: Reviews

Medical Update: A Review Of Tuberculosis In 2023

TB has been a gradually diminishing presence in the United States for decades, and currently there are only 2.4 cases per hundred thousand people in our country.

When I was in medical school, TB was still a big problem, and we learned about the fever, night sweats, weight loss and coughing up blood from active tuberculosis. With any of these symptoms, you should, of course, check with a physician.

These severe infections still happen but, currently, tuberculosis occurs primarily in immigrants from other countries, homeless people, prison inmates, people with Immune deficiency, such as cancel therapy and HIV infection.

TB is also  more common in Asians, Native Americans and Eskimos, and Hispanics.

The Ordinary middle class American citizen these days is unlikely to catch tuberculosis, unless they are exposed to somebody that has an active, open case, more likely in people described above.

On first contact, the Tubercle bacillus is almost always controlled by the immune system. Most of these primary cases are without symptoms, and after a few weeks could be picked up by an immune blood test, called the T-spot.TB, or the skin tuberculin test. The chest x-ray can also show a spot on the lung with primary tuberculosis. it is with reactivation that the severe symptoms of secondary TB, described above, can occur.

My own inclination would be to get tested with exposure to any of the groups mentioned above, especially if they have a cough.

Incidentally, there was a dip in tuberculosis incidence during the contagion versus COVID-19 pandemic, showing one more advantage in avoiding big, inside groups.

Catching tuberculosis at the earliest possible moment still continues to be important, especially since long drawn out disease in individuals who have defective immune systems has led to the development of drug resistant organisms.

—Dr. C.

Technology: New Head & Neck Cancer Treatments

Mayo Clinic (May 11, 2023) – In the U.S., HPV is linked to about 70% of throat and mouth cancers. And more than 70% of those cancers are diagnosed in men, according to the Centers for Disease Control and Prevention.

Treatment for throat and mouth cancers, also referred to as oropharyngeal or head and neck cancers, will depend on location and stage of the cancer as well as other factors. Dr. Phillip Pirgousis, a Mayo Clinic head and neck surgeon, says patients have safer, less invasive surgical treatments available to them thanks to ongoing innovation.

Heart Disease: A Surgeon’s View Of Aorta Surgery

Cleveland Clinic (MAY 9, 2023): Have you ever wondered what your surgeon thinks about when they are deciding if you need an operation?

Dr. Lars Svensson and Dr. Marijan Koprivanac discuss all things aorta, such as your past medical history, current health, and how your surgeon looks to the future to provide the best options for you.

READ MORE

HEALTH: HOW THE PANDEMIC RESHAPED AMERICAN LIFE

Wall Street Journal (May 5, 2023) – The alarms sounded in March 2020, and Americans cloistered at home, sheltering from a pandemic killing at times thousands a day. Many people free to work remotely left their big-city lives for suburbs and rural communities. Americans everywhere have settled into more homebound routines for meals and entertainment. Yet even with the deadly crisis fading, the U.S. has yet to recapture the level of happiness enjoyed before the virus SARS-CoV-2 transformed our world.

READ MORE AT WSJ

Insomnia: Can Cognitive Behavioral Therapy Help?

May 4, 2023: Difficulty initiating and maintaining sleep is a common problem for many patients. Over-the-counter sleeping aids are used by many and we commonly get asked for prescription medications to help with their sleep.

Unfortunately, the ideal sleeping medication doesn’t exist and many have potentially worrisome adverse effects, some produce daytime somnolence and others may have the potential to produce dependence.

Cognitive behavioral therapy is an alternative treatment option to pharmacologic therapy and is safe, can be easily taught, and offers an alternative to the many with chronic insomnia. In this podcast, we’ll discuss this innovative treatment option with sleep expert, Michael H. Silber, M.B.Ch.B., a neurologist at the Mayo Clinic. 

Heart Health: How The Aorta Functions (Yale)

Yale Medicine (April 29, 2023) – The aorta is a complex organ responsible for carrying blood to all organs and tissues in the body. Many disease conditions with catastrophic complications are associated with aortic pathologies, including aneurysm disease, aortic dissection, aortic ulcer and hematoma.

Care of patients with aortic diseases remains highly complex and requires the combined expertise of a multidisciplinary team of cardiovascular surgeons, neurologists, cardiac anesthesiologists, vascular surgeons, and specialized advanced practice providers.

Reviews: Young-Onset Colorectal Cancer

In the past decades the incidence of colorectal cancer (CRC) in people under the age of 50 years has increased, which is referred to as early-onset CRC or young-onset CRC (YO-CRC). YO-CRC is expected to account for 11% of colon cancers and 23% of rectal cancers by 2030. This trend is observed in different parts of the world and in both men and women. In 20% of patients with YO-CRC, a hereditary cancer syndrome is found as the underlying cause; however, in the majority of patients no genetic predisposition is present.

Beginning in the 1950s, major changes in lifestyle such as antibiotic use, low physical activity and obesity have affected the gut microbiome and may be an important factor in YO-CRC development. Owing to a lack of screening, patients with YO-CRC are often diagnosed with advanced-stage disease. Long-term treatment-related complications should be taken into account in these younger patients, making the more traditional sequential approaches of drug therapy not always the most appropriate option.

To better understand the underlying mechanism and define relationships between environmental factors and YO-CRC development, long-term prospective studies are needed with lifestyle data collected from childhood.

Read more

Coping With Irritable Bowel Syndrome (IBS)

Mayo Clinic (April 27, 2023) – Dr. Brian Lacy says irritable bowel syndrome, or IBS, is a chronic condition that affects the intestinal tract. It can cause painful stomach cramps, diarrhea and constipation.

IBS is now categorized as a disorder of gut-brain interaction, which means that there’s a problem with how the gut and brain communicate with each other. He says stress plays a key role. There’s no cure for IBS, but symptoms can be managed. Try eating smaller, more frequent meals, and exercising regularly. Deep breathing and yoga are also helpful to reduce stress.

READ MORE

STUDIES: ALCOHOL ABUSE INCREASES CHRONIC PAIN

Scripps Research (April 21, 2023) – Chronic alcohol consumption may make people more sensitive to pain through two different molecular mechanisms—one driven by alcohol intake and one by alcohol withdrawal. That is one new conclusion by scientists at Scripps Research on the complex links between alcohol and pain.

The research, published in the British Journal of Pharmacology on April 12, 2023, also suggests potential new drug targets for treating alcohol-associated chronic pain and hypersensitivity.

“There is an urgent need to better understand the two-way street between chronic pain and alcohol dependence,” says senior author Marisa Roberto, PhD, the Schimmel Family Chair of Molecular Medicine, and a professor of neuroscience at Scripps Research. “Pain is both a widespread symptom in patients suffering from alcohol dependence, as well as a reason why people are driven to drink again.”

Alcohol use disorder (AUD), which encompasses the conditions commonly called alcohol abuse, alcohol dependence and alcohol addiction, affects 29.5 million people in the U.S. according to the 2021 National Survey on Drug Use and Health.  Over time, AUD can trigger the development of numerous chronic diseases, including heart disease, stroke, liver disease and some cancers.

READ MORE AT SCRIPPS RESEARCH

Infographic: Binge Eating Disorder (BED) Diagnosis

Binge eating disorder (BED) is characterized by regular binge eating episodes during which individuals ingest comparably large amounts of food and experience loss of control over their eating behaviour. The worldwide prevalence of BED for the years 2018–2020 is estimated to be 0.6–1.8% in adult women and 0.3–0.7% in adult men. BED is commonly associated with obesity and with somatic and mental health comorbidities. People with BED experience considerable burden and impairments in quality of life, and, at the same time, BED often goes undetected and untreated.

READ MORE