Tag Archives: Harvard

Osteoarthritis: Increased Walking Lowers Knee Pain

People with knee osteoarthritis may reduce their risk of knee pain by walking more, according to a study published online June 8, 2022, by Arthritis & Rheumatology.

photo of three mature adults walking for fitness

Researchers looked at the walking habits of more than 1,200 people with knee osteoarthritis (average age 63, 45% men). They were asked how often they walked for exercise since age 50 and whether they had frequent knee pain. X-rays were done to assess structural knee damage.

The investigators first looked at participants who did not report regular knee pain. They found that among this group, those who walked for exercise were less likely to later develop knee pain (26%) at the follow-up eight years later compared with those who did not walk for exercise (37%).

Read more

Chronic Conditions: How To Prevent Kidney Stones

Dementia: Progress In Treatments (Harvard)

The potential benefit of nonpharmacologic memory-boosting strategies in the mild stages

One study from a group of Boston researchers examined 32 individuals with mild memory problems, half with mild cognitive impairment and half with mild Alzheimer’s disease dementia. They found that both groups improved their memory by simply thinking about the following question when learning new information: “What is one unique characteristic of this item or personal experience that differentiates it from others?” Another study by Boston researchers found that 19 individuals with mild cognitive impairment could improve their ability to remember items at a virtual supermarket by simply thinking systematically about whether items were already in their cupboard before putting them in their shopping cart. Larger studies are needed, however, to determine if such memory strategies are generalizable.

Music, pets, robots, and the environment in the moderate to severe stages

Similarly, there are many nonpharmacological treatments that appear to provide comfort and reduce agitation in individuals with moderate to severe dementia, but larger and more rigorous studies are needed to prove or disprove their efficacy, and thereby promote more widespread utilization.

  • A group of Portuguese clinicians and researchers reviewed more than 100 studies evaluating music-based interventions for people with dementia who had agitation or other behavioral and psychological symptoms of dementia, finding that the vast majority were efficacious with little or no side effects.
  • A team of neurologists from Florida reviewed the effects of dog therapy and ownership, finding that both were safe and effective approaches to treat chronic and progressive neurological disorders.
  • Other researchers found reductions in anxiety and psychoactive medication use when robot pets were given to individuals with dementia.
  • A review of the built environment (the architecture of the home or facility) concluded that “specific design interventions are beneficial to the outcomes of people with dementia.”

Knee Osteoarthritis: New Study Shows Telehealth Visit Benefits (Harvard)

Back Pain: The Symptoms And Causes Of Sciatica

Most sciatica is caused by problems that affect the L4L5, or S1 nerve roots. The nerve may be compressed or irritated, usually because it’s being rubbed by a disc, bone, joint, or ligament. The resulting inflammation makes the tis­sues and the nerves more sensitive and the pain feel worse.

Damage to or pinching of the sciatic nerve, or the nerves that feed into it, can have several causes.

Herniated disc

One of the most common causes of sciatica is a herniated disc in the lower part of the spine. It’s also called a slipped disc, though there’s no slipping going on.

Spinal discs are tucked between the vertebrae, where they act as cushions to keep the bones from touching one another. The discs absorb all the forces placed on the spine from walking, running, sitting, twisting, lifting, and every other activ­ity we do. They also absorb forces from falls, collisions, and other accidents.

Spinal stenosis

The spinal canal protects the spinal cord and the nerves that run up and down the spine. Spinal stenosis is the narrowing of the spinal canal. When this occurs, nerves can be compressed, causing pain. Because the lumbar verte­brae undergo the most consistent stress and support the most weight, lumbar stenosis is the most common type of spinal stenosis.

Spondylolisthesis

The bones of the spine are stacked on top of one another, separated by discs. Spondylolisthesis occurs when one spinal bone slips forward in relation to the bone below it. When the L4 vertebra moves over the L5 vertebra, it can cause a kink in the spinal canal leading to pressure on a nerve root and sciatica.

Read more

Brain Health: Endurance Exercise Raises Cognition

Health: Consequences Of Too Little Sleep (Harvard)

Medicine: Is Metformin A Wonder Drug? (Harvard)

HARVARD STUDY: VITAMIN D LOWERS THE RISK OF YOUNG-ONSET COLORECTAL CANCER

COMMENTARY:

Vitamin D has many beneficial effects, but my comments will be restricted to the effect of vitamin D on cancer.

Interest in this association was started by the observation that certain cancers are less common near the equator, where there is more sunlight exposure, and therefore more natural vitamin D generation in your skin.
The most information on cancer in humans Is available on colorectal, breast, prostate, and pancreatic cancer. Colorectal cancer, highlighted DWW our posting, is the only cancer that apparently is affected by vitamin D.

Several studies have suggested that vitamin D can decrease cancer cell growth, stimulate cell death, and reduce cancer blood vessel formation. Increasing cell death, or apoptosis, is what interests me the most, since this is one of the factors which increases inflammation in aging.

The infographics stated that only 300 international units of vitamin D is necessary to produce a 50 Percent reduction in cancer, and that a healthy diet generally supplies this.

I personally take 5000 international units vitamin D. This produces a blood level of about 60 ng/mL, and what the NFL recommends to keep their players healthy, and well within the maximum recommended level of 120 ng/milliliter.

Excessive vitamin D can produce an elevated calcium blood level, and mine is within normal limits. I take the higher dose because of vitamin D’s other effects, such is benefiting the immune system in a time of Conid-19.

I suggest that you get a vitamin D blood level, and also a calcium blood level if you elect to take more of this useful vitamin.

–Dr. C

Read more