Tag Archives: HPV

THE DOCTORS 101 CHRONIC SYMPTOMS & CONDITIONS #36: WARTS

Warts are so common as to have become a metaphor for any blemish. I have had several warts in childhood, most likely because my immunity was immature along with the rest of me. They went away, as do most warts. I have had a few warts on and off since, since the HPV that produces them is so widespread.

My immune reaction took care of them, For some reason, I now have a wart between my toes that bears watching. Hopefully it will go away like the rest. Warts rarely become malignant, They can cause problems with breathing if they block the airway, such as the larynx (voice box) or bronchi (breathing tubes). I had such a case in my Allergy/respiratory disease practice that sounded like asthma to the referring Doctor.

Elderly people can develop a variety of skin bumps, that my grandmother called “moles”. In the past month, I have developed a reddish bump on my nose. It looks a lot like the “intradermal nevus” pictured in an accompanying article from “consultant360”. Seborrheic Keratoses are common, and I have some of those too. Of course,

I have a regular crop of scaly “actinic Keratoses” for my Dermatologist to freeze with liquid Nitrogen during my twice yearly visits to prevent them from developing into cancer. I have a suspicion that many home remedies for warts, and the scraping and freezing efforts of dermatologists merely stir up the infected cells in the lesion and incite the immune system to mop up.

Time will usually do the job, but they are often annoying and there is always the temptation to treat them.

–Dr. C.

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THE DOCTORS 101 CHRONIC SYMPTOMS & CONDITIONS #34: Human Papillomavirus

Human Papillomavirus, HPV, is a very successful Virus, from the microbial standpoint. It has been around for a long time, specializes in Humans, kills many fewer than it infects and becomes a chronic disease, even if 90% of infections resolve spontaneously within 2 years.

Human Papillomavirus (HPV)

HPV is a DNA Virus. Most of the strains, if they persist, become harmless nuisances, and cause “Verruca Vulgaris”, the common wart of the skin. The voicebox and windpipe area is rarely targeted, but warts can produce problems there because of the location. Non-malignant genital warts can also occur with certain serotypes.

A few members of the HPV family have evolved to generate premalignant lesions that can develop into CANCER. These strains are spread by Sexual contact. In Women, the CERVIX of the Uterus or the vagina are often involved. The anal area, back of the throat and the Lung are occasional sites in both sexes. In Men, the Penis is targeted.

Cancer is generally a delayed effect that occurs after a long infection. Some HPV strains, such a 16 and 18, have evolved to suppress the p53 gene, an ONCOGENE which protects us from malignant progression. Without this protection, a chance cancerous mutation can grow without restraint. Since HPV can invade only the deeper basal stem cells in the skin or lining mucous membranes, some minor trauma or break in the surface is needed to allow Viral entry.

If antibodies are present, the Virus is intercepted, and infection doesn’t take place. This discovery made Immunization with the Cancer-producing strains attractive. It is also why the immunization is recommended in Childhood, before Sexual activity begins. Immunization after the HPV is already inside the body is Ineffective.

The Virus is already in the Nucleus of infected cells and protected from the immune response. The recommendation is to get the immunization in childhood, and use condoms.

–Dr. C.

WOMEN’S HEALTH: HOW ‘HPV (HUMAN PAPILLOMAVIRUS) LINKS TO CERVICAL CANCER’

This video tells the story of Ana, a cervical cancer survivor, who encourages women to recognize abnormal Paps as an opportunity to speak to your doctor about gynecologic health.

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