Harvard Medical School – A 13-year international study in mice demonstrates that loss of epigenetic information, which influences how DNA is organized and regulated, can drive aging independently of changes to the genetic code itself.
It also shows that restoring the integrity of the epigenome reverses age-related symptoms.
Our new position paper with @worldheartfed summarises the relationship between obesity and cardiovascular disease (#CVD) mortality.
World Obesity Federation (January 2023) – The ongoing obesity epidemic represents a global public health crisis that contributes to poor health outcomes, reduced quality of life, and >2.8 million deaths each year. Obesity is relapsing, progressive, and heterogeneous. It is considered a chronic disease by the World Obesity Federation (WOF) and a chronic condition by the World Heart Federation (WHF).
People living with overweight/obesity are at greater risk for cardiovascular (CV) morbidity and mortality. Increased adiposity (body fat), particularly visceral/abdominal fat, is linked to CV risk and CV disease (CVD) via multiple direct and indirect pathophysiological mechanisms. The development of CVD is driven, in part, by obesity-related metabolic, endocrinologic, immunologic, structural, humoral, haemodynamic, and functional alterations.
The Lancet (January 2023) – For our 200th anniversary year we have identified five Spotlight subjects of particular importance. Watch as Richard Horton, Editor-in-Chief, and other Lancet Editors around the world outline these Spotlights and discuss priorities for the future of health.
This year, we draw attention to the most critical issues impacting health globally, the extraordinary people involved in tackling them, and the voices of those most impacted. For five Spotlights, we will run a programme of activities to bring these issues to life and convene the right people and resources in order to drive change in these areas.
Freethink – Robotics are helping make minimally invasive surgeries even less invasive. Case in point: single-port robotic surgery, a relatively new type of approach where a robotic system controlled by a human surgeon executes the procedure by making only one incision into the patient.
Although still relatively uncommon, single-port surgery has been gaining momentum in recent years. The benefits are noticeable. Compared to traditional surgery, single-port surgery might leave patients with shorter recovery times, less scarring, and overall better outcomes.
The technique is also transforming how surgeons think about and execute surgery itself. “It’s allowing us to do surgeries differently than we do with [multi-port surgery],” said Michael Stifelman, M.D., director of robotic surgery at Hackensack University Medical Center. “What every patient wants is to get back to their life. Single-port robotics is allowing us to get them to that point more quickly.”
Learn more about the future of single-port surgery in this episode of “Operation: Reimagine Surgery,” a Freethink original series produced in partnership with Intuitive, which created the world’s first commercially available robotic surgery system in the 1990s.
Sudden cardiac arrest (SCA) isn’t the same as a heart attack, though people often use the terms interchangeably. While both are life-threatening heart conditions, understanding the differences could be lifesaving.
When it comes to cardiac arrest versus a heart attack, it can be easy to get them confused. You may be wondering, Is cardiac arrest the same as a heart attack?
Both a heart attack and cardiac arrest can be scary and life-threatening medical conditions affecting your heart, but there are differences in how and why they occur.
A heart attack is caused by a blockage. It happens when an artery blocks the blood flow to your heart.
Cardiac arrest is an electrical issue. It occurs when quick, irregular impulses take over your heart’s rhythm.
People with multimorbidity (two or more coexisting conditions in an individual) are more likely to die prematurely, be admitted to hospital and have an increased length of stay than people with a single chronic condition.
Multimorbidity is also associated with poorer function and health-related quality of life (HRQOL), depression and intake of multiple drugs (polypharmacy) and greater socioeconomic costs. Most health care is designed to treat individual conditions rather than providing comprehensive, person-centreed care, which often leads to fragmented and sometimes contradictory care for people with multimorbidity and increases their treatment burden. Moreover, treating one condition at a time is inefficient and unsatisfactory for both people with multimorbidity and their health-care providers.
Daniela Hernandez | WSJ – Getting the flu can increase the risk of getting a second infection, including strep throat. WSJ’S Daniela Hernandez explains the science behind that, plus what it means for the rest of the winter and how we can protect ourselves so the tripledemic doesn’t get worse.
Video timeline: 0:24 – Flu Damage 1:25 – Lower population immunity 2:03 – Who’s most vulnerable? 3:05 – How can we protect ourselves?
Cleveland Clinic – In living donor liver transplantation a portion of a donor’s healthy liver is transplanted into a recipient in need. Living donor liver transplantation is possible because the liver, unlike any other organ in the body, has the ability to regenerate (regrow). Most regeneration of both the donor’s and recipient’s livers occurs within the first 8 weeks.
All potential donors will undergo a complete medical and psychosocial evaluation. Not everyone is suitable or eligible to become a living liver donor based on a number of factors such as pre-existing medical conditions, psychosocial concerns, or liver size. Donating an organ is a personal decision that should only be made after becoming fully informed about its potential risks and benefits.