Tag Archives: Cortisol

DR. C’S JOURNAL: STRESS & ADRENALINE (EPINEPHRINE)

Adrenaline (epinephrine) was first discovered when the adrenal gland was ground up and injected, producing an increase in the pulse rate. it has a myriad of uses, and often In emergencies when speed of injection is of great importance. You may you recall the controversy when the price of EpiPen was jacked up to ridiculous levels.

Adrenaline is intimately involved with cortisol in emergency stress reactions. Adrenaline increases cortisol production, and cortisol increases the number of cell membrane adrenoreceptors. Adrenaline is much more rapidly acting, and cortisol sticks around for a while keeping the stress response going.

Adrenaline produces a myriad of responses that are beneficial when you’re trying to run away from that sabertooth tiger. Just like cortisol, it increases the pulse rate, blood pressure, blood sugar and heart rate. It opens up the bronchial tubes so you can breathe better, and also increases muscle strength and alertness, with a negative affect.

As mentioned in the article on cortisol, stress has a negative connotation at present, even though it was vital to our survival as a species. I can’t tell you how many shots of adrenaline I gave to my asthmatic patients. Medications to prevent asthma are much more numerous these days and adrenaline is rarely needed for Asthma any more.

Adrenaline  is still very useful, however, in cardiac arrest, and Anaphylactic reactions. You may recall having read about Anaphylactic reactions from the Propylene glycol in some Covid immunizations.
In the long run You will do better to keep your stress levels down. Try to avoid talking about family affairs, religion, and politics.

—Dr. C.

DR. C’S JOURNAL: Stress & The Effects Of Cortisol

Cortisol (hydrocortisone, 17-OH-corticosterone) is produced by stress, and is a bad word these days. When I was a practicing allergist, Cortisol worked wonders with asthma, and as a salve helped my patients with eczema.

It functions in the body as a key part of the stress reaction, which preparers the animal body for “Fight or flight”.  Cortisone raises the blood pressure, heart rate and blood sugar, and shuts down The immune system, which is not as necessary in times of emergency. It is this last function which helped my patients with asthma and eczema, which are diseases of excessive immune reactivity. You may have heard of the use of dexamethasone( A relative of cortisol ) in severe Covid, which is made worse by an excessive immune response.

Modern life is a pressure cooker, requiring continuous activity and deadlines. The blood Cortisone level, which is raised by stress, is helpful in the short term, but deleterious when persisting over the long term. The prolonged elevation of blood Pressure, blood sugar and heart rate, coupled with a decrease in bone and collagen formation can lead to all kinds of problems including weight gain, diabetes, cardiovascular problems, osteoporosis and mental decline.

Although  cortisol in the short term can enhance memory (think of flash – bulb memory), in the long run it decreases hippocampal function, impacting memory.

For these and other reasons, Modern Life makes it desirable to reduce stress and the accompanying elevation of cortisol . Our old friends, Proper sleep, diet and exercise are critical, and help activities such as laughter and yoga to reduce stress. The following reference will cover this in more detail.

—Dr. C.

THE DOCTORS 101 CHRONIC SYMPTOMS & CONDITIONS #30: ACNE (Vulgaris)

ACNE is almost a rite of passage in adolescents, although it is not totally restricted to the teen years; women may experience acne during pregnancy, or at the time of menopause. It afflicts about 90% of kids during their PUBERTAL growth spurt, though is moderate or severe in only 15%.

Acne is caused by PLUGGING of the sebaceous glands of the skin. Infection by certain skin BACTERIA follows. Check the accompanying video for a description of the battle between the “Good guys”, Staph epidermidis and Cutibacterium acnes, vs. the bad guy, Proprionibactrium
acnes.

Acne tends to run in families. The steroid HORMONES like Testosterone and Cortisone promote Acne. STRESS tends to chronically raise Cortisol and is a factor in Acne, and many chronic illnesses as well.

A person who is having trouble with Acne should avoid sweets and greasy foods, which is a good idea for everybody. Skin cleansers, using salicylic or azelaic acids and benzoyl peroxide may help, and creams containing retinoic acid derivatives may be useful..

The doctor may prescribe an antibiotic like tetracycline in resistant cases. Cystic acne may be scarring, but otherwise “the zits” depart with the pubertal years.

–Dr. C.

Further reading at Mayo Clinic